Child and family health research studies
Contact usImproving the quality of life for children and families
With research specific to children, we can better understand, prevent and treat childhood illnesses. We also study pregnancy-related conditions and explore ways to improve maternal and paternal health. This research enables us to address medical needs and raise the standards of health care for families in our communities and beyond.
Why you should enroll in a research study
- Study volunteers enrolled in a clinical study receive an extra layer of medical care with frequent follow-up and progress assessments.
- Study volunteers participating in clinical trials may achieve better outcomes than those not enrolled in a study.
- Study volunteers get access to the latest treatments long before they may become widely available.
- As a result of your own experience or that of a loved one, you may want to shape the future of health care for yourself and others.
Find a child and family health study
Purpose: The purpose of this study is to learn more about a medicine called nipocalimab to see if it can help protect unborn babies from a serious blood problem called HDFN. HDFN happens when a mother's blood attacks her baby's blood cells. The study will check if the medicine is safe and works well.
Research leader: Suwan Mehra, MD
Region: Greater Chicago IL
IRB number: IRB00104576
Purpose: The purpose of this study is to learn more about a nasal spray medicine called etripamil. We want to see if it can safely stop fast heartbeats in children with heart rhythm disorder called Paroxysmal Supraventricular Tachycardia (PSVT). We will also help find the best dose for different age groups. Doctors want to learn how the medicine works in kids and if it causes any side effects.
Research leader: Frank Zimmerman, MD
Region: Greater Chicago IL
IRB number: IRB00104694
Purpose: The purpose of this study is to find the best way to help teens feel better and manage stress. Teens and their parents will try parts of an online program that teaches coping skills. The goal is to see which parts work best to prevent sadness or low mood.
Research leader: Huma Khan, MD
Region: Greater Chicago IL
IRB number: IRB00104773
Purpose: The study aims to find out if the study drug, levocarnitine, can reduce severe liver damage caused by chemotherapy in patients with certain cancers.
Research leader: Rebecca McFall, MD
Region: Greater Chicago IL
IRB number: IRB00105839
Purpose: The purpose of this study is to learn more about two new cancer drugs. We want to see if these drugs work better than the usual treatment for people with early-stage Hodgkin lymphoma. During the study, everyone will start with standard chemotherapy and then get assigned to either the usual treatment or the new drugs. The goal is to find out which treatment works best and has fewer side effects.
Research leader: Rebecca McFall, MD
Region: Greater Chicago IL
IRB number: IRB00106140
Purpose: This study collects health information from people with cystic fibrosis (CF) or related conditions. The goal is to help doctors and researchers better understand CF and improve care. The information is stored in a secure registry and used to study health trends and treatments.
Research leader: Kimberly Watts, MD
Region: Greater Chicago IL
IRB number: IRB00106937
Purpose: The purpose of this study is to learn more about a new medicine called DFMO for patients with neuroblastoma. We want to see if the medicine can help keep neuroblastoma from coming back after treatment. The medicine is taken by mouth every day for two years. Our researchers also want to learn how safe the medicine is and how well patients can handle it.
Research leader: Rebecca McFall, MD
Region: Greater Chicago IL
IRB number: IRB00107038
Purpose: The purpose of this study is to learn more about a medicine called vedolizumab. We want to see if this medicine helps children with moderate to severe Crohn's disease feel better. We also want to see if the medicine is safe and how children's bodies handle it. The study includes kids ages 2 to 17 who have not gotten better with other treatments.
Research leader: Kiranmai Gorla, MD
Region: Greater Chicago IL
IRB number: IRB00107175
Purpose: The purpose of this study is to learn more about a new heart valve called the SAPIEN 3. We want to see how well this valve replacement works in people who have problems with the valve that connects the heart to the lungs. The valve is placed using a less invasive method instead of open-heart surgery. Doctors will check how the valve works over 5 years.
Research leader: Alexander Javois, MD
Region: Greater Chicago IL
IRB number: IRB00107199
Purpose: The purpose of this study is to learn more about a new device to close a hole in the heart called an atrial septal defect (ASD). The goal is to see if the device is safe and works well. Doctors hope it will help the heart heal without leaving metal behind.
Research leader: Alexander Javois, MD
Region: Greater Chicago IL
IRB number: IRB00107200
Purpose: The purpose of this study is to find out which of two programs can help teens better manage stress and avoid depression. One program is a group that meets in person or online, and the other is a website teens use on their own. The goal is to help teens feel better and stay healthy.
Research leader: Huma Khan, MD
Region: Greater Chicago IL
IRB number: IRB00107203
Purpose: The purpose of this study is to find better ways to diagnose, treat, and prevent cancers in children, adolescents, and young adults. To do so, we will collect information and samples from children and young adults who have cancer.
Research leader: Rebecca McFall, MD
Region: Greater Chicago IL
IRB number: IRB00107245
Purpose: The purpose of this study is to learn if children and young adults with low-risk germ cell tumors need more treatment after surgery. We are checking if just watching them closely works as well as giving them more medicine or another surgery.
Research leader: Rebecca McFall, MD
Region: Greater Chicago IL
IRB number: IRB00107251
Purpose: The purpose of this study is to look at better ways to treat a type of liver cancer called hepatoblastomas among children. Our researchers want to see if using fewer or different medicines can still cure the cancer while causing fewer side effects. The goal is to help children live longer and feel better during and after treatment.
Research leader: Rebecca McFall, MD
Region: Greater Chicago IL
IRB number: IRB00107257
Purpose: This study compares two ways of giving chemotherapy to people with advanced germ cell tumors. One way gives the medicine faster to see if it works better and is still safe. The goal is to find out if the faster treatment helps more without causing more side effects.
Research leader: Rebecca McFall, MD
Region: Greater Chicago IL
IRB number: IRB00107259
Purpose: The purpose of this study is to see how well a new heart valve called Medtronic Harmony Transcatheter Pulmonary Valve (TPV) works. The valve is placed without open-heart surgery in people who have heart problems from birth. Doctors want to see if the valve helps the heart work better and improves daily life.
Research leader: Dhaval Patel, MD
Region: Greater Chicago IL
IRB number: IRB00107277
Purpose: The purpose of this study is to test bone marrow and blood from people with leukemia. We want to see if the leukemia has certain traits that could help the doctors decide what medicine might be best for you. This study will also collect information about your treatment for leukemia. We want to see how well it worked and find out if there were any long-term side effects.
Research leader: Rebecca McFall, MD
Region: Greater Chicago IL
IRB number: IRB00112497
Purpose: The purpose of this study is to learn more about a drug called DFMO. We want to see if it helps children with a serious brain tumor called medulloblastoma. The goal is to find out if DFMO can keep the cancer from coming back after treatment. Doctors also want to learn more about how safe the drug is for children and young adults,
Research leader: Rebecca McFall, MD
Region: Greater Chicago IL
IRB number: IRB00121901